{"id":4210,"date":"2026-05-19T07:10:04","date_gmt":"2026-05-19T07:10:04","guid":{"rendered":"https:\/\/limitlessbiochem.mx\/?post_type=product&#038;p=4210"},"modified":"2026-06-11T15:35:38","modified_gmt":"2026-06-11T15:35:38","slug":"tirz-glp-2-10mg-lyophilized-powder","status":"publish","type":"product","link":"https:\/\/limitlessbiochem.mx\/en\/product\/tirz-glp-2-10mg-lyophilized-powder\/","title":{"rendered":"TIRZ (GLP-2) 10mg"},"content":{"rendered":"<div style=\"font-family: 'Random Grotesque Standard','Poppins',sans-serif; font-size: 14.5px; color: #061735; line-height: 1.6;\">\n<p style=\"margin-bottom: 12px;\"><strong style=\"font-family: 'Random Grotesque Bold','Poppins',sans-serif;\">TIRZ (GLP-2) 10 mg<\/strong><br \/>\nresearch-grade<br \/>\n<strong style=\"font-family: 'Random Grotesque Bold','Poppins',sans-serif;\">lyophilized peptide powder<\/strong><br \/>\nsupplied in a glass vial. This compound, also referred to as<br \/>\n<strong style=\"font-family: 'Random Grotesque Bold','Poppins',sans-serif;\">LY3298176<\/strong>,<br \/>\nis an incretin peptide analog studied as a dual agonist at the GIP (glucose-dependent insulinotropic polypeptide) and GLP-1<br \/>\n(glucagon-like peptide-1) receptors in experimental metabolic research models.<\/p>\n<div style=\"border-left: 4px solid #0075ED; background: #F5FAFF; padding: 10px 12px; border-radius: 10px; margin-bottom: 14px; color: #061735; font-family: 'Random Grotesque Standard','Poppins',sans-serif;\"><strong style=\"font-family: 'Random Grotesque Bold','Poppins',sans-serif;\">Research Use Only:<\/strong><br \/>\nAll products are intended exclusively for laboratory and scientific research. Not for human or veterinary use.<\/div>\n<div style=\"font-family: 'Random Grotesque Standard','Poppins',sans-serif; border-radius: 16px; overflow: hidden; box-shadow: 0 2px 0 rgba(6,23,53,0.12); background: linear-gradient(135deg,#00B4FF 0%,#0075ED 100%); color: #f4f2e9; margin: 18px 0;\">\n<div style=\"padding: 15px 20px;\">\n<p><!-- Purity (no visible COA link, so generic high-purity wording) --><\/p>\n<div style=\"display: flex; border-bottom: 1px solid rgba(251,250,246,0.35);\">\n<div style=\"flex: 1; padding: 10px 14px; color: #fbfaf6;\">Purity<\/div>\n<div style=\"flex: 2; padding: 10px 14px;\">High-purity research grade<\/div>\n<\/div>\n<p><!-- Form --><\/p>\n<div style=\"display: flex; border-bottom: 1px solid rgba(251,250,246,0.35);\">\n<div style=\"flex: 1; padding: 10px 14px; color: #fbfaf6;\">Form<\/div>\n<div style=\"flex: 2; padding: 10px 14px;\">Lyophilized peptide powder<\/div>\n<\/div>\n<p><!-- Content (per vial) --><\/p>\n<div style=\"display: flex; border-bottom: 1px solid rgba(251,250,246,0.35);\">\n<div style=\"flex: 1; padding: 10px 14px; color: #fbfaf6;\">Content<\/div>\n<div style=\"flex: 2; padding: 10px 14px;\">10 mg TIRZ (GLP-2) per vial<\/div>\n<\/div>\n<p><!-- Packaging --><\/p>\n<div style=\"display: flex; border-bottom: 1px solid rgba(251,250,246,0.35);\">\n<div style=\"flex: 1; padding: 10px 14px; color: #fbfaf6;\">Packaging<\/div>\n<div style=\"flex: 2; padding: 10px 14px;\">Glass vial with sterile closure<\/div>\n<\/div>\n<p><!-- Storage --><\/p>\n<div style=\"display: flex; border-bottom: 1px solid rgba(251,250,246,0.35);\">\n<div style=\"flex: 1; padding: 10px 14px; color: #fbfaf6;\">Storage<\/div>\n<div style=\"flex: 2; padding: 10px 14px;\">Store lyophilized at 2\u20138 \u00b0C (desiccated, protect from light)<\/div>\n<\/div>\n<p><!-- Molecular formula --><\/p>\n<div style=\"display: flex; border-bottom: 1px solid rgba(251,250,246,0.35);\">\n<div style=\"flex: 1; padding: 10px 14px; color: #fbfaf6;\">Molecular formula<\/div>\n<div style=\"flex: 2; padding: 10px 14px;\">C<sub>225<\/sub>H<sub>348<\/sub>N<sub>48<\/sub>O<sub>68<\/sub><\/div>\n<\/div>\n<p><!-- Molecular weight --><\/p>\n<div style=\"display: flex; border-bottom: 1px solid rgba(251,250,246,0.35);\">\n<div style=\"flex: 1; padding: 10px 14px; color: #fbfaf6;\">Molecular weight<\/div>\n<div style=\"flex: 2; padding: 10px 14px;\">~4813.5 g\u00b7mol\u207b\u00b9<\/div>\n<\/div>\n<p><!-- Sequence \/ Structure --><\/p>\n<div style=\"display: flex; border-bottom: 1px solid rgba(251,250,246,0.35);\">\n<div style=\"flex: 1; padding: 10px 14px; color: #fbfaf6;\">Sequence \/ structure<\/div>\n<div style=\"flex: 2; padding: 10px 14px;\">Tyr-{Aib}-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-{Aib}-Leu-Asp-Lys-{diacid-C20-\u03b3Glu-(AEEA)2}-Ala-Ala-Gln-{Aib}-Ala-Phe-Ile-Glu-Tyr-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH<sub>2<\/sub><\/div>\n<\/div>\n<p><!-- CAS number --><\/p>\n<div style=\"display: flex;\">\n<div style=\"flex: 1; padding: 10px 14px; color: #fbfaf6;\">CAS number<\/div>\n<div style=\"flex: 2; padding: 10px 14px;\">2023788-19-2<\/div>\n<\/div>\n<\/div>\n<\/div>\n<p><!-- BAC note for lyophilized peptide vials --><\/p>\n<div style=\"border-left: 4px solid #0075ED; background: #F5FAFF; padding: 10px 12px; border-radius: 10px; margin: 12px 0 10px; color: #061735;\"><strong style=\"font-family: 'Random Grotesque Bold','Poppins',sans-serif;\"><br \/>\nIn laboratory workflows, lyophilized research peptides are typically handled with suitable sterile diluents such as bacteriostatic water (BAC).<br \/>\n<\/strong><br \/>\nFor a compatible research-only solvent, see<br \/>\n<a style=\"text-decoration: underline; color: #0075ed;\" href=\"\/products\/bacteriostatic-water-10ml\" target=\"_blank\" rel=\"noopener\"><br \/>\nBacteriostatic water \u2013 10 ml<br \/>\n<\/a>.<\/div>\n<h3 style=\"font-size: 16.5px; font-weight: 800; margin: 12px 0 6px; font-family: 'Random Grotesque Bold','Poppins',sans-serif;\">Research Overview<\/h3>\n<p style=\"margin: 0 0 10px;\">TIRZ (GLP-2), also known as LY3298176, is a synthetic incretin peptide analog investigated as a dual agonist at the GIP and GLP-1 receptors.<br \/>\nIn experimental in vitro and in vivo models it is used to explore how concurrent activation of these incretin pathways affects glucose handling,<br \/>\ninsulin secretion, glucagon regulation, gastric emptying, appetite-related signaling and broader metabolic endpoints.<\/p>\n<h4 style=\"font-size: 15px; font-weight: bold; margin: 10px 0 5px; font-family: 'Random Grotesque Bold','Poppins',sans-serif;\">Primary Research Areas<\/h4>\n<ul style=\"margin: 0 0 10px 18px; padding-left: 18px; font-family: 'Random Grotesque Standard','Poppins',sans-serif;\">\n<li style=\"margin: 4px 0;\"><strong style=\"font-family: 'Random Grotesque Bold','Poppins',sans-serif;\">Dual GIP and GLP-1 receptor agonism:<\/strong><br \/>\nused in studies assessing combined activation of GIP and GLP-1 receptors and its impact on incretin signaling cascades in metabolic research models.<\/li>\n<li style=\"margin: 4px 0;\"><strong style=\"font-family: 'Random Grotesque Bold','Poppins',sans-serif;\">Glucose control and insulin sensitivity:<\/strong><br \/>\napplied in experimental systems examining insulin secretion, glucagon suppression, glycemic excursions and insulin sensitivity under controlled<br \/>\nlaboratory conditions.<\/li>\n<li style=\"margin: 4px 0;\"><strong style=\"font-family: 'Random Grotesque Bold','Poppins',sans-serif;\">Body weight and adiposity models:<\/strong><br \/>\ninvestigated in preclinical models of body weight regulation, adipose tissue remodeling and energy balance in the context of incretin pathway modulation.<\/li>\n<li style=\"margin: 4px 0;\"><strong style=\"font-family: 'Random Grotesque Bold','Poppins',sans-serif;\">Appetite regulation and gastric emptying:<\/strong><br \/>\nused to study satiety signaling, food intake behavior and gastric emptying rate in animal and cellular models related to appetite control.<\/li>\n<li style=\"margin: 4px 0;\"><strong style=\"font-family: 'Random Grotesque Bold','Poppins',sans-serif;\">Cardiometabolic health markers:<\/strong><br \/>\nincluded in broader cardiometabolic research evaluating lipid parameters, inflammatory markers and vascular endpoints associated with incretin-based modulation.<\/li>\n<\/ul>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>TIRZ (GLP-2) 10 mg research-grade lyophilized peptide powder supplied in a glass vial. This compound, also referred to as LY3298176, [&hellip;]<\/p>\n","protected":false},"featured_media":4211,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"_lb_product_label_url":"https:\/\/drive.google.com\/file\/d\/196IwDQhua6AT8JMEUJP_vcd3R9AWJtxN\/view?usp=drive_link","_lb_product_label_size":"45x20","_lb_product_label_width":"45","_lb_product_label_height":"20"},"product_brand":[41],"product_cat":[1124,1133,1117,1125],"product_tag":[],"class_list":["post-4210","product","type-product","status-publish","has-post-thumbnail","product_brand-limitlessbiochem","product_cat-all-products","product_cat-new-products","product_cat-peptides","product_cat-powders","desktop-align-left","tablet-align-left","mobile-align-left","first","instock","featured","purchasable","product-type-simple","product-backorders-allowed"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>TIRZ (GLP-2) 10 mg \u2013 lyophilized powder | Limitless BioChem<\/title>\n<meta name=\"description\" content=\"Purchase TIRZ (GLP-2) 10 mg lyophilized peptide powder in a glass vial. 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High-purity research-grade incretin peptide (LY3298176) studied in dual GIP\/GLP-1 receptor agonism, glucose control, weight management and metabolic health models.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/limitlessbiochem.mx\/en\/product\/tirz-glp-2-10mg-lyophilized-powder\/","og_locale":"en_US","og_type":"article","og_title":"TIRZ (GLP-2) 10 mg \u2013 lyophilized powder | Limitless BioChem","og_description":"Purchase TIRZ (GLP-2) 10 mg lyophilized peptide powder in a glass vial. 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